STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (310 aa)    
Predicted Functional Partners:
B4167_0759
Citrate synthase (si); Belongs to the citrate synthase family.
  
 0.990
B4167_0760
Isocitrate dehydrogenase [NADP].
  
 
 0.960
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.960
B4167_0749
NADP-dependent malic enzyme.
  
 0.938
Pyc
Pyruvate carboxyl transferase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 0.935
B4167_3481
Malate synthase; Belongs to the malate synthase family.
   
 0.930
mqo
Malate:quinone oxidoreductase.
   
 0.923
B4167_0581
Aspartate aminotransferase.
  
 0.923
pckA
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
  
 
 0.921
B4167_3766
Methylmalonyl-CoA mutase.
    
 0.863
Your Current Organism:
Bacillus thermoamylovorans
NCBI taxonomy Id: 35841
Other names: B. thermoamylovorans, Bacillus sp. LMG 18084, Bacillus sp. R-6546, Bacillus sp. R-7440, Bacillus sp. R-7764, LMG 18084, LMG:18084, Lactobacter thermoamylovorans, strain DKP
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