STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFS14780.1Uncharacterized membrane protein YkvI. (378 aa)    
Predicted Functional Partners:
SFS14788.1
Two-component system, response regulator YcbB.
       0.773
grdB
Glycine reductase.
 
     0.688
SFS14765.1
Glycine reductase.
 
     0.675
SFS14750.1
Hypothetical protein.
 
     0.664
SFS14756.1
Transcriptional regulator, TetR family.
 
     0.574
trxB
Thioredoxin reductase (NADPH).
 
     0.565
SFS14827.1
Betaine reductase.
 
     0.534
SFS14811.1
Glycine reductase complex selenoprotein A.
 
     0.494
grdA
Betaine reductase; In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine. By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state. Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination.
 
     0.471
SFS14804.1
Thioredoxin 1.
 
     0.457
Your Current Organism:
Clostridium citroniae
NCBI taxonomy Id: 358743
Other names: CCUG 52203, Clostridium citroniae Warren et al. 2007, DSM 19261, [. citroniae, [Clostridium] citroniae, strain RMA 16102
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