Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DF19_00535Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa)    
Predicted Functional Partners:
DF19_00530
Nitrogen fixation protein NifU; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
sufC
Cysteine desulfurase; Part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.995
DF19_00550
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.994
DF19_00555
Fe-S cluster assembly protein SufB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.991
DF19_00525
Metal-sulfur cluster biosynthetic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.969
DF19_25885
Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.894
DF19_27225
Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...]
  
 
 0.892
DF19_31970
Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.890
DF19_00545
Rieske (2Fe-2S) protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.885
DF19_03790
Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.882
Your Current Organism:
Streptomyces olindensis
NCBI taxonomy Id: 358823
Other names: S. olindensis
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