STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DF19_01465Imidazole glycerol phosphate synthase; Catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)    
Predicted Functional Partners:
DF19_01475
Phosphoribosyl isomerase; Catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide and the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)anthranilate; involved in histidine and tryptophan biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.999
DF19_01480
Imidazole glycerol phosphate synthase subunit HisH; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
DF19_01490
Imidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
DF19_01500
Histidinol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
DF19_01455
phosphoribosyl-AMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.998
DF19_01495
Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.998
DF19_05455
ATP phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.998
hisE
phosphoribosyl-ATP pyrophosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.996
DF19_01365
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.970
DF19_39335
Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.969
Your Current Organism:
Streptomyces olindensis
NCBI taxonomy Id: 358823
Other names: S. olindensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.