Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
DF19_03415Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)    
Predicted Functional Partners:
DF19_30310
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.914
DF19_39090
Thioredoxin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.812
DF19_11180
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.807
DF19_25475
Thioredoxin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.715
DF19_05440
3,4-dihydroxy-2-butanone 4-phosphate synthase; Bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.699
DF19_01365
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.696
DF19_16520
uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.695
groEL
Molecular chaperone GroEL; 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; Derived by autom [...]
   
 
 0.686
groEL-2
Molecular chaperone GroEL; 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; Derived by autom [...]
   
 
 0.686
DF19_40325
Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.674
Your Current Organism:
Streptomyces olindensis
NCBI taxonomy Id: 358823
Other names: S. olindensis
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