Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DF19_19760Nitroreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa)    
Predicted Functional Partners:
DF19_32905
2-phospho-L-lactate transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.767
DF19_19755
Lysine transporter LysE; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.751
DF19_32910
F420-0--gamma-glutamyl ligase; Catalyzes the addition of gamma linked glutamate to 7,8-didemethyl-8-hydroxy-5-deazariboflavin coenzyme F420-0); Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.744
DF19_27225
Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...]
  
 0.739
DF19_15725
5,10-methylene tetrahydromethanopterin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.734
DF19_32120
F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.730
DF19_42755
F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.730
DF19_39365
Luciferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.727
DF19_40260
Luciferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.723
DF19_38190
5,10-methylene tetrahydromethanopterin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.708
Your Current Organism:
Streptomyces olindensis
NCBI taxonomy Id: 358823
Other names: S. olindensis
Server load: low (16%) [HD]