Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
guaDGuanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (436 aa)    
Predicted Functional Partners:
XdhA
Xanthine dehydrogenase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.983
xdhB
Xanthine dehydrogenase molybdopterin binding subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.977
AQS61083.1
Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.965
hpt
Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
  
 0.924
AQS63000.1
Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.910
gpt
Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
     
 0.902
PgeF
Polyphenol oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
XdhC
Xanthine dehydrogenase accessory protein XdhC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.784
UraH
Hydroxyisourate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.750
puuE
Allantoinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.726
Your Current Organism:
Agrobacterium rhizogenes
NCBI taxonomy Id: 359
Other names: A. rhizogenes, ATCC 11325, Agrobacterium biovar 2, Agrobacterium genomic group 10, Agrobacterium genomic species 10, Agrobacterium genomosp. 10, Agrobacterium rhizogenes (RI plasmid PRI1724), Agrobacterium rhizogenes (RI plasmid PRI8196), Agrobacterium rhizogenes (RI plasmid PRIA4B), CFBP 5520, CIP 104328, DSM 30148, ICMP 5794, IFO 13257, JCM 20919, LMG 150, LMG:150, NBRC 13257, NCPPB 2991, Rhizobium rhizogenes, Rhizobium sp. LMG 9509
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