Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AQS62059.1Heme A synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)    
Predicted Functional Partners:
AQS62465.1
Cytochrome c oxidase assembly protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.994
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 
 0.994
AQS62462.1
Cytochrome c oxidase assembly protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.955
AQS62993.1
Surfeit locus 1 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.946
AQS61294.1
Cytochrome c oxidase assembly protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.904
AQS61157.1
Cytochrome c1; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.847
CoxB
Cytochrome c oxidase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.789
AQS61894.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.774
CyoA
Ubiquinol oxidase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.769
ctaD
Cytochrome c oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
 
 
 0.756
Your Current Organism:
Agrobacterium rhizogenes
NCBI taxonomy Id: 359
Other names: A. rhizogenes, ATCC 11325, Agrobacterium biovar 2, Agrobacterium genomic group 10, Agrobacterium genomic species 10, Agrobacterium genomosp. 10, Agrobacterium rhizogenes (RI plasmid PRI1724), Agrobacterium rhizogenes (RI plasmid PRI8196), Agrobacterium rhizogenes (RI plasmid PRIA4B), CFBP 5520, CIP 104328, DSM 30148, ICMP 5794, IFO 13257, JCM 20919, LMG 150, LMG:150, NBRC 13257, NCPPB 2991, Rhizobium rhizogenes, Rhizobium sp. LMG 9509
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