node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CN09_00005 | CN09_00010 | CN09_00005 | CN09_00010 | Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology | Aminomethyltransferase; Belongs to the GcvT family | 0.747 |
CN09_00005 | CN09_17085 | CN09_00005 | CN09_17085 | Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology | Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family | 0.816 |
CN09_00005 | CN09_23555 | CN09_00005 | CN09_23555 | Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology | Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.729 |
CN09_00005 | gcvP | CN09_00005 | CN09_06885 | Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein | 0.908 |
CN09_00005 | glyA | CN09_00005 | CN09_10385 | Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | 0.879 |
CN09_00005 | guaA | CN09_00005 | CN09_14055 | Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology | Gmp synthase; Catalyzes the synthesis of GMP from XMP | 0.861 |
CN09_00005 | guaB | CN09_00005 | CN09_16005 | Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology | inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth | 0.859 |
CN09_00005 | purD | CN09_00005 | CN09_16590 | Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology | Phosphoribosylamine--glycine ligase; Belongs to the GARS family | 0.729 |
CN09_00005 | purH | CN09_00005 | CN09_17805 | Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional purine biosynthesis protein PurH; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.826 |
CN09_00005 | ribB | CN09_00005 | CN09_16765 | Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate | 0.862 |
CN09_00010 | CN09_00005 | CN09_00010 | CN09_00005 | Aminomethyltransferase; Belongs to the GcvT family | Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.747 |
CN09_00010 | gcvP | CN09_00010 | CN09_06885 | Aminomethyltransferase; Belongs to the GcvT family | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein | 0.999 |
CN09_00010 | glyA | CN09_00010 | CN09_10385 | Aminomethyltransferase; Belongs to the GcvT family | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | 0.627 |
CN09_17085 | CN09_00005 | CN09_17085 | CN09_00005 | Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family | Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.816 |
CN09_17085 | CN09_23555 | CN09_17085 | CN09_23555 | Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family | Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
CN09_17085 | guaA | CN09_17085 | CN09_14055 | Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family | Gmp synthase; Catalyzes the synthesis of GMP from XMP | 0.999 |
CN09_17085 | guaB | CN09_17085 | CN09_16005 | Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family | inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth | 0.908 |
CN09_17085 | purH | CN09_17085 | CN09_17805 | Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional purine biosynthesis protein PurH; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.918 |
CN09_17085 | ribB | CN09_17085 | CN09_16765 | Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate | 0.999 |
CN09_23555 | CN09_00005 | CN09_23555 | CN09_00005 | Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology | Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.729 |