node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CN09_01550 | CN09_01555 | CN09_01550 | CN09_01555 | Hypothetical protein; Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology | Cobalamin biosynthesis protein CobW; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.950 |
CN09_01550 | CN09_07710 | CN09_01550 | CN09_07710 | Hypothetical protein; Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | 0.514 |
CN09_01550 | cysE | CN09_01550 | CN09_01545 | Hypothetical protein; Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.822 |
CN09_01555 | CN09_01550 | CN09_01555 | CN09_01550 | Cobalamin biosynthesis protein CobW; Derived by automated computational analysis using gene prediction method: Protein Homology | Hypothetical protein; Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.950 |
CN09_01555 | cysE | CN09_01555 | CN09_01545 | Cobalamin biosynthesis protein CobW; Derived by automated computational analysis using gene prediction method: Protein Homology | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.820 |
CN09_03380 | CN09_08460 | CN09_03380 | CN09_08460 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | Cysteine synthase; CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.675 |
CN09_03380 | cysE | CN09_03380 | CN09_01545 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.889 |
CN09_03380 | cysK | CN09_03380 | CN09_14200 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.675 |
CN09_03380 | guaA | CN09_03380 | CN09_14055 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | Gmp synthase; Catalyzes the synthesis of GMP from XMP | 0.999 |
CN09_03380 | ispDF | CN09_03380 | CN09_07765 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) | 0.999 |
CN09_03380 | polA | CN09_03380 | CN09_13050 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity | 0.627 |
CN09_07710 | CN09_01550 | CN09_07710 | CN09_01550 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | Hypothetical protein; Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.514 |
CN09_07710 | CN09_08460 | CN09_07710 | CN09_08460 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | Cysteine synthase; CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.917 |
CN09_07710 | cysE | CN09_07710 | CN09_01545 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.913 |
CN09_07710 | cysK | CN09_07710 | CN09_14200 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.917 |
CN09_07710 | ispDF | CN09_07710 | CN09_07765 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) | 0.999 |
CN09_07710 | polA | CN09_07710 | CN09_13050 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity | 0.999 |
CN09_08460 | CN09_03380 | CN09_08460 | CN09_03380 | Cysteine synthase; CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.675 |
CN09_08460 | CN09_07710 | CN09_08460 | CN09_07710 | Cysteine synthase; CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | 0.917 |
CN09_08460 | cysE | CN09_08460 | CN09_01545 | Cysteine synthase; CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.977 |