node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CN09_03025 | CN09_03380 | CN09_03025 | CN09_03380 | Glycine cleavage system protein t; Belongs to the GcvT family | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.970 |
CN09_03025 | CN09_07815 | CN09_03025 | CN09_07815 | Glycine cleavage system protein t; Belongs to the GcvT family | Branched-chain alpha-keto acid dehydrogenase subunit e2; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) | 0.970 |
CN09_03025 | CN09_08190 | CN09_03025 | CN09_08190 | Glycine cleavage system protein t; Belongs to the GcvT family | Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.973 |
CN09_03025 | CN09_27945 | CN09_03025 | CN09_27945 | Glycine cleavage system protein t; Belongs to the GcvT family | Dihydrolipoyl dehydrogenase; Catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.973 |
CN09_03025 | gcvH | CN09_03025 | CN09_06890 | Glycine cleavage system protein t; Belongs to the GcvT family | The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein | 0.995 |
CN09_03025 | gcvP | CN09_03025 | CN09_06885 | Glycine cleavage system protein t; Belongs to the GcvT family | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein | 0.999 |
CN09_03025 | gor | CN09_03025 | CN09_06270 | Glycine cleavage system protein t; Belongs to the GcvT family | Glutathione reductase; Maintains high levels of reduced glutathione | 0.973 |
CN09_03025 | lpdA | CN09_03025 | CN09_07805 | Glycine cleavage system protein t; Belongs to the GcvT family | E3 component of alpha keto acid dehydrogenase complexes LpdC; forms a homodimer; binds one molecule of FAD monomer; catalyzes NAD+-dependent oxidation of dihydrolipoyl cofactors that are covalently linked to the E2 component; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.973 |
CN09_03025 | nnrD | CN09_03025 | CN09_07485 | Glycine cleavage system protein t; Belongs to the GcvT family | Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.999 |
CN09_03025 | prs | CN09_03025 | CN09_04275 | Glycine cleavage system protein t; Belongs to the GcvT family | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P) | 0.972 |
CN09_03380 | CN09_03025 | CN09_03380 | CN09_03025 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | Glycine cleavage system protein t; Belongs to the GcvT family | 0.970 |
CN09_03380 | CN09_07815 | CN09_03380 | CN09_07815 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | Branched-chain alpha-keto acid dehydrogenase subunit e2; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) | 0.999 |
CN09_03380 | CN09_08190 | CN09_03380 | CN09_08190 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
CN09_03380 | CN09_27945 | CN09_03380 | CN09_27945 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | Dihydrolipoyl dehydrogenase; Catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
CN09_03380 | gcvH | CN09_03380 | CN09_06890 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein | 0.999 |
CN09_03380 | gcvP | CN09_03380 | CN09_06885 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein | 0.890 |
CN09_03380 | gor | CN09_03380 | CN09_06270 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | Glutathione reductase; Maintains high levels of reduced glutathione | 0.999 |
CN09_03380 | lpdA | CN09_03380 | CN09_07805 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | E3 component of alpha keto acid dehydrogenase complexes LpdC; forms a homodimer; binds one molecule of FAD monomer; catalyzes NAD+-dependent oxidation of dihydrolipoyl cofactors that are covalently linked to the E2 component; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
CN09_03380 | nnrD | CN09_03380 | CN09_07485 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.948 |
CN09_03380 | prs | CN09_03380 | CN09_04275 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P) | 0.999 |