ureA protein (Agrobacterium rhizogenes) - STRING interaction network

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ureA

Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the urease gamma subunit family (100 aa)

Predicted Functional Partners:

ureC

0.999

ureB

0.999

CN09_03065

0.999

ureD

0.997

ureE

0.997

ureF

0.996

ureG

0.990

CN09_03080

0.886

CN09_18390

0.886

guaA

0.882

Your Current Organism:

Agrobacterium rhizogenes

NCBI taxonomy Id: 359
Other names: A. rhizogenes, ATCC 11325, Agrobacterium biovar 2, Agrobacterium genomic group 10, Agrobacterium genomic species 10, Agrobacterium genomosp. 10, Agrobacterium rhizogenes, Agrobacterium rhizogenes (RI plasmid PRI1724), Agrobacterium rhizogenes (RI plasmid PRI8196), Agrobacterium rhizogenes (RI plasmid PRIA4B), CFBP 5520, CIP 104328, DSM 30148, ICMP 5794, IFO 13257, JCM 20919, LMG 150, NBRC 13257, NCPPB 2991, Rhizobium rhizogenes, Rhizobium sp. LMG 9509

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CN09_03065	CN09_03080	CN09_03065	CN09_03080	ATPase; Derived by automated computational analysis using gene prediction method- Protein Homology	Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the binding-protein-dependent transport system permease family	0.683
CN09_03065	guaA	CN09_03065	CN09_14055	ATPase; Derived by automated computational analysis using gene prediction method- Protein Homology	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	0.759
CN09_03065	ureA	CN09_03065	CN09_03100	ATPase; Derived by automated computational analysis using gene prediction method- Protein Homology	Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the urease gamma subunit family	0.999
CN09_03065	ureB	CN09_03065	CN09_03105	ATPase; Derived by automated computational analysis using gene prediction method- Protein Homology	Urease subunit beta; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem [...]	0.999
CN09_03065	ureC	CN09_03065	CN09_03115	ATPase; Derived by automated computational analysis using gene prediction method- Protein Homology	Urease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method- Protein Homology	0.999
CN09_03065	ureD	CN09_03065	CN09_03095	ATPase; Derived by automated computational analysis using gene prediction method- Protein Homology	Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	0.990
CN09_03065	ureE	CN09_03065	CN09_03130	ATPase; Derived by automated computational analysis using gene prediction method- Protein Homology	Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly	0.992
CN09_03065	ureF	CN09_03065	CN09_03135	ATPase; Derived by automated computational analysis using gene prediction method- Protein Homology	Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	0.999
CN09_03065	ureG	CN09_03065	CN09_03140	ATPase; Derived by automated computational analysis using gene prediction method- Protein Homology	Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG	0.987
CN09_03080	CN09_03065	CN09_03080	CN09_03065	Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the binding-protein-dependent transport system permease family	ATPase; Derived by automated computational analysis using gene prediction method- Protein Homology	0.683
CN09_03080	ureA	CN09_03080	CN09_03100	Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the binding-protein-dependent transport system permease family	Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the urease gamma subunit family	0.886
CN09_03080	ureB	CN09_03080	CN09_03105	Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the binding-protein-dependent transport system permease family	Urease subunit beta; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem [...]	0.865
CN09_03080	ureC	CN09_03080	CN09_03115	Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the binding-protein-dependent transport system permease family	Urease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method- Protein Homology	0.862
CN09_03080	ureD	CN09_03080	CN09_03095	Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the binding-protein-dependent transport system permease family	Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	0.927
CN09_03080	ureE	CN09_03080	CN09_03130	Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the binding-protein-dependent transport system permease family	Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly	0.608
CN09_03080	ureF	CN09_03080	CN09_03135	Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the binding-protein-dependent transport system permease family	Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	0.845
CN09_03080	ureG	CN09_03080	CN09_03140	Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the binding-protein-dependent transport system permease family	Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG	0.814
CN09_18390	ureA	CN09_18390	CN09_03100	Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology	Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the urease gamma subunit family	0.886
CN09_18390	ureB	CN09_18390	CN09_03105	Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology	Urease subunit beta; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem [...]	0.821
CN09_18390	ureC	CN09_18390	CN09_03115	Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology	Urease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method- Protein Homology	0.795

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