pfp protein (Agrobacterium rhizogenes) - STRING interaction network

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pfp

Pyrophosphate--fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions (403 aa)

Predicted Functional Partners:

CN09_03380

0.996

CN09_17085

0.988

pgi

0.986

eno

0.985

CN09_24995

0.984

CN09_02010

0.983

CN09_17570

0.977

CN09_06325

0.971

CN09_14585

0.971

polA

0.968

Your Current Organism:

Agrobacterium rhizogenes

NCBI taxonomy Id: 359
Other names: A. rhizogenes, ATCC 11325, Agrobacterium biovar 2, Agrobacterium genomic group 10, Agrobacterium genomic species 10, Agrobacterium genomosp. 10, Agrobacterium rhizogenes, Agrobacterium rhizogenes (RI plasmid PRI1724), Agrobacterium rhizogenes (RI plasmid PRI8196), Agrobacterium rhizogenes (RI plasmid PRIA4B), CFBP 5520, CIP 104328, DSM 30148, ICMP 5794, IFO 13257, JCM 20919, LMG 150, NBRC 13257, NCPPB 2991, Rhizobium rhizogenes, Rhizobium sp. LMG 9509

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CN09_02010	CN09_03380	CN09_02010	CN09_03380	Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology	0.978
CN09_02010	CN09_06325	CN09_02010	CN09_06325	Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family	Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology	0.996
CN09_02010	CN09_14585	CN09_02010	CN09_14585	Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family	Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology	0.996
CN09_02010	CN09_17085	CN09_02010	CN09_17085	Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family	Pyruvate, phosphate dikinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family	0.869
CN09_02010	CN09_24995	CN09_02010	CN09_24995	Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family	Acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology	0.883
CN09_02010	eno	CN09_02010	CN09_07835	Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family	Enolase; Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family	0.990
CN09_02010	pfp	CN09_02010	CN09_04965	Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family	Pyrophosphate--fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	0.983
CN09_02010	pgi	CN09_02010	CN09_15010	Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family	Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family	0.985
CN09_02010	polA	CN09_02010	CN09_13050	Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	0.999
CN09_03380	CN09_02010	CN09_03380	CN09_02010	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology	Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family	0.978
CN09_03380	CN09_06325	CN09_03380	CN09_06325	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology	Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology	0.999
CN09_03380	CN09_14585	CN09_03380	CN09_14585	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology	Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology	0.999
CN09_03380	CN09_17085	CN09_03380	CN09_17085	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology	Pyruvate, phosphate dikinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family	0.999
CN09_03380	CN09_24995	CN09_03380	CN09_24995	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology	Acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology	0.999
CN09_03380	eno	CN09_03380	CN09_07835	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology	Enolase; Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family	0.999
CN09_03380	pfp	CN09_03380	CN09_04965	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology	Pyrophosphate--fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	0.996
CN09_03380	pgi	CN09_03380	CN09_15010	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology	Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family	0.985
CN09_03380	polA	CN09_03380	CN09_13050	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	0.918
CN09_06325	CN09_02010	CN09_06325	CN09_02010	Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology	Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family	0.996
CN09_06325	CN09_03380	CN09_06325	CN09_03380	Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology	0.999

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