STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CN09_04970Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology (236 aa)    
Predicted Functional Partners:
grxD
Belongs to the glutaredoxin family. Monothiol subfamily
   
 0.999
CN09_07090
Nitrogen fixation protein NifU; Derived by automated computational analysis using gene prediction method: Protein Homology
  
 
 0.997
sufA
Fes assembly scaffold sufa; Belongs to the HesB/IscA family
  
 0.996
erpA
Heme biosynthesis protein hemy; Belongs to the HesB/IscA family
  
 0.996
groL
Molecular chaperone groel; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
   
 0.992
CN09_27060
Molecular chaperone groel; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
   
 0.992
CN09_16975
Belongs to the peptidase M16 family
   
  0.987
CN09_27940
Belongs to the peptidase M16 family
   
  0.987
grpE
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions be [...]
    
 0.984
dnaK
Molecular chaperone dnak; Acts as a chaperone
  
 0.983
Your Current Organism:
Agrobacterium rhizogenes
NCBI taxonomy Id: 359
Other names: A. rhizogenes, ATCC 11325, Agrobacterium biovar 2, Agrobacterium genomic group 10, Agrobacterium genomic species 10, Agrobacterium genomosp. 10, Agrobacterium rhizogenes (RI plasmid PRI1724), Agrobacterium rhizogenes (RI plasmid PRI8196), Agrobacterium rhizogenes (RI plasmid PRIA4B), CFBP 5520, CIP 104328, DSM 30148, ICMP 5794, IFO 13257, JCM 20919, LMG 150, NBRC 13257, NCPPB 2991, Rhizobium rhizogenes, Rhizobium sp. LMG 9509
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