node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CN09_03380 | CN09_03985 | CN09_03380 | CN09_03985 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
CN09_03380 | CN09_15290 | CN09_03380 | CN09_15290 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | Hemagglutinin; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
CN09_03380 | gcvP | CN09_03380 | CN09_06885 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family | 0.977 |
CN09_03380 | polA | CN09_03380 | CN09_13050 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity | 0.918 |
CN09_03380 | rnhB | CN09_03380 | CN09_16450 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA- DNA hybrids | 0.999 |
CN09_03380 | thyA | CN09_03380 | CN09_05290 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis | 0.933 |
CN09_03380 | ung | CN09_03380 | CN09_02810 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine | 0.957 |
CN09_03985 | CN09_03380 | CN09_03985 | CN09_03380 | Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
CN09_03985 | CN09_05380 | CN09_03985 | CN09_05380 | Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis | 0.869 |
CN09_03985 | CN09_15290 | CN09_03985 | CN09_15290 | Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology | Hemagglutinin; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.553 |
CN09_03985 | gcvP | CN09_03985 | CN09_06885 | Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family | 0.613 |
CN09_03985 | polA | CN09_03985 | CN09_13050 | Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity | 0.999 |
CN09_03985 | rnhB | CN09_03985 | CN09_16450 | Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA- DNA hybrids | 0.429 |
CN09_03985 | tdk | CN09_03985 | CN09_03920 | Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology | Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.796 |
CN09_03985 | thyA | CN09_03985 | CN09_05290 | Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis | 0.950 |
CN09_03985 | ung | CN09_03985 | CN09_02810 | Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine | 0.999 |
CN09_05380 | CN09_03985 | CN09_05380 | CN09_03985 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis | Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.869 |
CN09_05380 | CN09_15290 | CN09_05380 | CN09_15290 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis | Hemagglutinin; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.797 |
CN09_05380 | dut | CN09_05380 | CN09_14245 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family | 0.516 |
CN09_05380 | gcvP | CN09_05380 | CN09_06885 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family | 0.750 |