node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CN09_03380 | gltB | CN09_03380 | CN09_01825 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.897 |
CN09_03380 | guaA | CN09_03380 | CN09_14055 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | Gmp synthase; Catalyzes the synthesis of GMP from XMP | 0.999 |
CN09_03380 | guaB | CN09_03380 | CN09_16005 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth | 0.999 |
CN09_03380 | ispDF | CN09_03380 | CN09_07765 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) | 0.999 |
CN09_03380 | polA | CN09_03380 | CN09_13050 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity | 0.627 |
CN09_03380 | pyrG | CN09_03380 | CN09_07170 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | Ctp synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates | 0.976 |
CN09_03380 | ribD | CN09_03380 | CN09_10375 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate | 0.999 |
gltB | CN09_03380 | CN09_01825 | CN09_03380 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.897 |
gltB | guaA | CN09_01825 | CN09_14055 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology | Gmp synthase; Catalyzes the synthesis of GMP from XMP | 0.999 |
gltB | guaB | CN09_01825 | CN09_16005 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology | inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth | 0.999 |
gltB | polA | CN09_01825 | CN09_13050 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology | In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity | 0.999 |
gltB | pyrG | CN09_01825 | CN09_07170 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology | Ctp synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates | 0.999 |
gltB | ribD | CN09_01825 | CN09_10375 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate | 0.999 |
gltB | rpoB | CN09_01825 | CN09_08935 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology | Dna-directed rna polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates | 0.999 |
guaA | CN09_03380 | CN09_14055 | CN09_03380 | Gmp synthase; Catalyzes the synthesis of GMP from XMP | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
guaA | gltB | CN09_14055 | CN09_01825 | Gmp synthase; Catalyzes the synthesis of GMP from XMP | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
guaA | guaB | CN09_14055 | CN09_16005 | Gmp synthase; Catalyzes the synthesis of GMP from XMP | inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth | 0.999 |
guaA | ispDF | CN09_14055 | CN09_07765 | Gmp synthase; Catalyzes the synthesis of GMP from XMP | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) | 0.768 |
guaA | polA | CN09_14055 | CN09_13050 | Gmp synthase; Catalyzes the synthesis of GMP from XMP | In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity | 0.999 |
guaA | pyrG | CN09_14055 | CN09_07170 | Gmp synthase; Catalyzes the synthesis of GMP from XMP | Ctp synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates | 0.999 |