purM protein (Agrobacterium rhizogenes) - STRING interaction network

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purM

Phosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method- Protein Homology (357 aa)

Predicted Functional Partners:

purD

0.999

CN09_10515

0.999

guaA

0.999

guaB

0.999

nnrD

0.999

CN09_01825

0.999

purF

0.998

purQ

0.996

purH

0.995

purE

0.994

Your Current Organism:

Agrobacterium rhizogenes

NCBI taxonomy Id: 359
Other names: A. rhizogenes, ATCC 11325, Agrobacterium biovar 2, Agrobacterium genomic group 10, Agrobacterium genomic species 10, Agrobacterium genomosp. 10, Agrobacterium rhizogenes, Agrobacterium rhizogenes (RI plasmid PRI1724), Agrobacterium rhizogenes (RI plasmid PRI8196), Agrobacterium rhizogenes (RI plasmid PRIA4B), CFBP 5520, CIP 104328, DSM 30148, ICMP 5794, IFO 13257, JCM 20919, LMG 150, NBRC 13257, NCPPB 2991, Rhizobium rhizogenes, Rhizobium sp. LMG 9509

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CN09_01825	CN09_10515	CN09_01825	CN09_10515	Glutamate synthase; Derived by automated computational analysis using gene prediction method- Protein Homology	Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	0.843
CN09_01825	guaA	CN09_01825	CN09_14055	Glutamate synthase; Derived by automated computational analysis using gene prediction method- Protein Homology	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	0.999
CN09_01825	guaB	CN09_01825	CN09_16005	Glutamate synthase; Derived by automated computational analysis using gene prediction method- Protein Homology	Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family	0.593
CN09_01825	nnrD	CN09_01825	CN09_07485	Glutamate synthase; Derived by automated computational analysis using gene prediction method- Protein Homology	Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family	0.912
CN09_01825	purD	CN09_01825	CN09_16590	Glutamate synthase; Derived by automated computational analysis using gene prediction method- Protein Homology	Phosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the GARS family	0.906
CN09_01825	purE	CN09_01825	CN09_02065	Glutamate synthase; Derived by automated computational analysis using gene prediction method- Protein Homology	N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	0.999
CN09_01825	purF	CN09_01825	CN09_10810	Glutamate synthase; Derived by automated computational analysis using gene prediction method- Protein Homology	Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	0.999
CN09_01825	purM	CN09_01825	CN09_10510	Glutamate synthase; Derived by automated computational analysis using gene prediction method- Protein Homology	Phosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method- Protein Homology	0.999
CN09_10515	CN09_01825	CN09_10515	CN09_01825	Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	Glutamate synthase; Derived by automated computational analysis using gene prediction method- Protein Homology	0.843
CN09_10515	guaA	CN09_10515	CN09_14055	Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	0.989
CN09_10515	guaB	CN09_10515	CN09_16005	Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family	0.981
CN09_10515	nnrD	CN09_10515	CN09_07485	Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family	0.984
CN09_10515	purD	CN09_10515	CN09_16590	Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	Phosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the GARS family	0.995
CN09_10515	purE	CN09_10515	CN09_02065	Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	0.782
CN09_10515	purF	CN09_10515	CN09_10810	Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	0.955
CN09_10515	purH	CN09_10515	CN09_17805	Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	Bifunctional purine biosynthesis protein PurH; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method- Protein Homology	0.997
CN09_10515	purM	CN09_10515	CN09_10510	Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	Phosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method- Protein Homology	0.999
CN09_10515	purQ	CN09_10515	CN09_06680	Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	Phosphoribosylformylglycinamidine synthase subunit PurQ; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought t [...]	0.709
guaA	CN09_01825	CN09_14055	CN09_01825	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	Glutamate synthase; Derived by automated computational analysis using gene prediction method- Protein Homology	0.999
guaA	CN09_10515	CN09_14055	CN09_10515	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	0.989

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