| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CN09_10375 | CN09_15290 | CN09_10375 | CN09_15290 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family | Hemagglutinin; Derived by automated computational analysis using gene prediction method- Protein Homology | 0.999 |
| CN09_10375 | grpE | CN09_10375 | CN09_14485 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- dependent [...] | 0.999 |
| CN09_10375 | hrcA | CN09_10375 | CN09_14475 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons | 0.408 |
| CN09_10375 | htpG | CN09_10375 | CN09_32535 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family | Chaperone protein HtpG; Molecular chaperone. Has ATPase activity | 0.764 |
| CN09_15290 | CN09_10375 | CN09_15290 | CN09_10375 | Hemagglutinin; Derived by automated computational analysis using gene prediction method- Protein Homology | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family | 0.999 |
| CN09_15290 | CN09_21890 | CN09_15290 | CN09_21890 | Hemagglutinin; Derived by automated computational analysis using gene prediction method- Protein Homology | Chaperone protein DnaK; Acts as a chaperone | 0.960 |
| CN09_15290 | CN09_27210 | CN09_15290 | CN09_27210 | Hemagglutinin; Derived by automated computational analysis using gene prediction method- Protein Homology | Chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family | 0.715 |
| CN09_15290 | CN09_34040 | CN09_15290 | CN09_34040 | Hemagglutinin; Derived by automated computational analysis using gene prediction method- Protein Homology | Chaperone protein DnaK; Acts as a chaperone | 0.960 |
| CN09_15290 | dnaJ | CN09_15290 | CN09_34045 | Hemagglutinin; Derived by automated computational analysis using gene prediction method- Protein Homology | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.532 |
| CN09_15290 | grpE | CN09_15290 | CN09_14485 | Hemagglutinin; Derived by automated computational analysis using gene prediction method- Protein Homology | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- dependent [...] | 0.992 |
| CN09_15290 | hslU | CN09_15290 | CN09_17460 | Hemagglutinin; Derived by automated computational analysis using gene prediction method- Protein Homology | ATP-dependent protease ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis | 0.719 |
| CN09_15290 | htpG | CN09_15290 | CN09_32535 | Hemagglutinin; Derived by automated computational analysis using gene prediction method- Protein Homology | Chaperone protein HtpG; Molecular chaperone. Has ATPase activity | 0.800 |
| CN09_21890 | CN09_15290 | CN09_21890 | CN09_15290 | Chaperone protein DnaK; Acts as a chaperone | Hemagglutinin; Derived by automated computational analysis using gene prediction method- Protein Homology | 0.960 |
| CN09_21890 | CN09_27210 | CN09_21890 | CN09_27210 | Chaperone protein DnaK; Acts as a chaperone | Chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family | 0.911 |
| CN09_21890 | dnaJ | CN09_21890 | CN09_34045 | Chaperone protein DnaK; Acts as a chaperone | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.988 |
| CN09_21890 | grpE | CN09_21890 | CN09_14485 | Chaperone protein DnaK; Acts as a chaperone | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- dependent [...] | 0.983 |
| CN09_21890 | hrcA | CN09_21890 | CN09_14475 | Chaperone protein DnaK; Acts as a chaperone | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons | 0.896 |
| CN09_21890 | hslU | CN09_21890 | CN09_17460 | Chaperone protein DnaK; Acts as a chaperone | ATP-dependent protease ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis | 0.870 |
| CN09_21890 | hslV | CN09_21890 | CN09_17465 | Chaperone protein DnaK; Acts as a chaperone | ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery | 0.874 |
| CN09_21890 | htpG | CN09_21890 | CN09_32535 | Chaperone protein DnaK; Acts as a chaperone | Chaperone protein HtpG; Molecular chaperone. Has ATPase activity | 0.919 |
