node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CN09_17475 | coaA | CN09_17475 | CN09_17500 | Hypothetical protein; Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology | Pantothenate kinase; Catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.804 |
CN09_17475 | hisA | CN09_17475 | CN09_17485 | Hypothetical protein; Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-hosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.929 |
CN09_17475 | hisB | CN09_17475 | CN09_17470 | Hypothetical protein; Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology | Imidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.902 |
CN09_17475 | hisE | CN09_17475 | CN09_17495 | Hypothetical protein; Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology | Phosphoribosyl-ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.889 |
CN09_17475 | hisF | CN09_17475 | CN09_17490 | Hypothetical protein; Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology | Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit | 0.902 |
CN09_17475 | hisH | CN09_17475 | CN09_17480 | Hypothetical protein; Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology | Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF | 0.952 |
CN09_17475 | hslU | CN09_17475 | CN09_17460 | Hypothetical protein; Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology | Atp-dependent protease; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis | 0.740 |
CN09_17475 | hslV | CN09_17475 | CN09_17465 | Hypothetical protein; Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology | Peptidase; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery | 0.789 |
coaA | CN09_17475 | CN09_17500 | CN09_17475 | Pantothenate kinase; Catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology | Hypothetical protein; Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.804 |
coaA | guaA | CN09_17500 | CN09_14055 | Pantothenate kinase; Catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology | Gmp synthase; Catalyzes the synthesis of GMP from XMP | 0.865 |
coaA | hisA | CN09_17500 | CN09_17485 | Pantothenate kinase; Catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-hosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.950 |
coaA | hisB | CN09_17500 | CN09_17470 | Pantothenate kinase; Catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology | Imidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.768 |
coaA | hisE | CN09_17500 | CN09_17495 | Pantothenate kinase; Catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology | Phosphoribosyl-ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.980 |
coaA | hisF | CN09_17500 | CN09_17490 | Pantothenate kinase; Catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology | Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit | 0.955 |
coaA | hisH | CN09_17500 | CN09_17480 | Pantothenate kinase; Catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology | Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF | 0.886 |
coaA | hslU | CN09_17500 | CN09_17460 | Pantothenate kinase; Catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology | Atp-dependent protease; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis | 0.550 |
coaA | hslV | CN09_17500 | CN09_17465 | Pantothenate kinase; Catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology | Peptidase; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery | 0.595 |
coaA | nnrD | CN09_17500 | CN09_07485 | Pantothenate kinase; Catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology | Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.984 |
guaA | coaA | CN09_14055 | CN09_17500 | Gmp synthase; Catalyzes the synthesis of GMP from XMP | Pantothenate kinase; Catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.865 |
guaA | hisA | CN09_14055 | CN09_17485 | Gmp synthase; Catalyzes the synthesis of GMP from XMP | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-hosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.936 |