node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CN09_06715 | CN09_10515 | CN09_06715 | CN09_10515 | Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate | 0.697 |
CN09_06715 | guaA | CN09_06715 | CN09_14055 | Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily | Gmp synthase; Catalyzes the synthesis of GMP from XMP | 0.999 |
CN09_06715 | guaB | CN09_06715 | CN09_16005 | Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily | inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth | 0.999 |
CN09_06715 | purA | CN09_06715 | CN09_02930 | Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP | 0.997 |
CN09_06715 | purD | CN09_06715 | CN09_16590 | Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily | Phosphoribosylamine--glycine ligase; Belongs to the GARS family | 0.946 |
CN09_06715 | purH | CN09_06715 | CN09_17805 | Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional purine biosynthesis protein PurH; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.996 |
CN09_06715 | ribD | CN09_06715 | CN09_10375 | Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate | 0.464 |
CN09_10515 | CN09_06715 | CN09_10515 | CN09_06715 | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate | Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily | 0.697 |
CN09_10515 | guaA | CN09_10515 | CN09_14055 | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate | Gmp synthase; Catalyzes the synthesis of GMP from XMP | 0.999 |
CN09_10515 | guaB | CN09_10515 | CN09_16005 | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate | inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth | 0.986 |
CN09_10515 | polA | CN09_10515 | CN09_13050 | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate | In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity | 0.954 |
CN09_10515 | purA | CN09_10515 | CN09_02930 | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP | 0.752 |
CN09_10515 | purD | CN09_10515 | CN09_16590 | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate | Phosphoribosylamine--glycine ligase; Belongs to the GARS family | 0.995 |
CN09_10515 | purH | CN09_10515 | CN09_17805 | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional purine biosynthesis protein PurH; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.997 |
CN09_10515 | ribD | CN09_10515 | CN09_10375 | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate | 0.899 |
guaA | CN09_06715 | CN09_14055 | CN09_06715 | Gmp synthase; Catalyzes the synthesis of GMP from XMP | Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily | 0.999 |
guaA | CN09_10515 | CN09_14055 | CN09_10515 | Gmp synthase; Catalyzes the synthesis of GMP from XMP | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate | 0.999 |
guaA | guaB | CN09_14055 | CN09_16005 | Gmp synthase; Catalyzes the synthesis of GMP from XMP | inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth | 0.999 |
guaA | polA | CN09_14055 | CN09_13050 | Gmp synthase; Catalyzes the synthesis of GMP from XMP | In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity | 0.999 |
guaA | purA | CN09_14055 | CN09_02930 | Gmp synthase; Catalyzes the synthesis of GMP from XMP | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP | 0.999 |