modC protein (Agrobacterium rhizogenes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

modC

Molybdenum import ATP-binding protein ModC; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family (357 aa)

Predicted Functional Partners:

CN09_17965

0.996

CN09_17970

0.987

CN09_17955

0.923

moaA

0.884

mobA

0.875

CN09_16470

0.840

CN09_07710

0.838

moaC

0.831

CN09_26325

0.823

CN09_14290

0.809

Your Current Organism:

Agrobacterium rhizogenes

NCBI taxonomy Id: 359
Other names: A. rhizogenes, ATCC 11325, Agrobacterium biovar 2, Agrobacterium genomic group 10, Agrobacterium genomic species 10, Agrobacterium genomosp. 10, Agrobacterium rhizogenes, Agrobacterium rhizogenes (RI plasmid PRI1724), Agrobacterium rhizogenes (RI plasmid PRI8196), Agrobacterium rhizogenes (RI plasmid PRIA4B), CFBP 5520, CIP 104328, DSM 30148, ICMP 5794, IFO 13257, JCM 20919, LMG 150, NBRC 13257, NCPPB 2991, Rhizobium rhizogenes, Rhizobium sp. LMG 9509

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CN09_07710	CN09_16470	CN09_07710	CN09_16470	Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme; In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family	Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin	0.999
CN09_07710	CN09_17965	CN09_07710	CN09_17965	Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme; In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family	Molybdate ABC transporter permease; Derived by automated computational analysis using gene prediction method- Protein Homology	0.849
CN09_07710	moaA	CN09_07710	CN09_06205	Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme; In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family	GTP 3’,8-cyclase; Catalyzes the cyclization of GTP to (8S)-3’,8-cyclo-7,8- dihydroguanosine 5’-triphosphate; Belongs to the radical SAM superfamily. MoaA family	0.999
CN09_07710	moaC	CN09_07710	CN09_07235	Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme; In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family	Cyclic pyranopterin monophosphate synthase; Catalyzes the conversion of (8S)-3’,8-cyclo-7,8- dihydroguanosine 5’-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family	0.999
CN09_07710	mobA	CN09_07710	CN09_06185	Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme; In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family	Molybdenum cofactor guanylyltransferase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family	0.999
CN09_07710	modC	CN09_07710	CN09_17960	Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme; In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family	Molybdenum import ATP-binding protein ModC; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family	0.838
CN09_14290	CN09_16470	CN09_14290	CN09_16470	Transporter; Derived by automated computational analysis using gene prediction method- Protein Homology	Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin	0.631
CN09_14290	CN09_17955	CN09_14290	CN09_17955	Transporter; Derived by automated computational analysis using gene prediction method- Protein Homology	LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method- Protein Homology	0.828
CN09_14290	CN09_17965	CN09_14290	CN09_17965	Transporter; Derived by automated computational analysis using gene prediction method- Protein Homology	Molybdate ABC transporter permease; Derived by automated computational analysis using gene prediction method- Protein Homology	0.841
CN09_14290	CN09_17970	CN09_14290	CN09_17970	Transporter; Derived by automated computational analysis using gene prediction method- Protein Homology	Molybdenum ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method- Protein Homology	0.958
CN09_14290	CN09_26325	CN09_14290	CN09_26325	Transporter; Derived by automated computational analysis using gene prediction method- Protein Homology	Nicotinate-nucleotide pyrophosphorylase; Catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the NadC/ModD family	0.666
CN09_14290	moaA	CN09_14290	CN09_06205	Transporter; Derived by automated computational analysis using gene prediction method- Protein Homology	GTP 3’,8-cyclase; Catalyzes the cyclization of GTP to (8S)-3’,8-cyclo-7,8- dihydroguanosine 5’-triphosphate; Belongs to the radical SAM superfamily. MoaA family	0.885
CN09_14290	moaC	CN09_14290	CN09_07235	Transporter; Derived by automated computational analysis using gene prediction method- Protein Homology	Cyclic pyranopterin monophosphate synthase; Catalyzes the conversion of (8S)-3’,8-cyclo-7,8- dihydroguanosine 5’-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family	0.732
CN09_14290	mobA	CN09_14290	CN09_06185	Transporter; Derived by automated computational analysis using gene prediction method- Protein Homology	Molybdenum cofactor guanylyltransferase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family	0.732
CN09_14290	modC	CN09_14290	CN09_17960	Transporter; Derived by automated computational analysis using gene prediction method- Protein Homology	Molybdenum import ATP-binding protein ModC; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family	0.809
CN09_16470	CN09_07710	CN09_16470	CN09_07710	Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin	Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme; In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family	0.999
CN09_16470	CN09_14290	CN09_16470	CN09_14290	Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin	Transporter; Derived by automated computational analysis using gene prediction method- Protein Homology	0.631
CN09_16470	CN09_17955	CN09_16470	CN09_17955	Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin	LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method- Protein Homology	0.766
CN09_16470	CN09_17965	CN09_16470	CN09_17965	Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin	Molybdate ABC transporter permease; Derived by automated computational analysis using gene prediction method- Protein Homology	0.839
CN09_16470	CN09_17970	CN09_16470	CN09_17970	Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin	Molybdenum ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method- Protein Homology	0.845

page 1 of 5

Network

Neighborhood

Experiments

Fusion

Textmining

Cooccurrence

Databases

Coexpression

© STRING Consortium 2020

Credits

Access

Info

About