node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CN09_07710 | CN09_23595 | CN09_07710 | CN09_23595 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | Precorrin 6a synthase; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A | 0.966 |
CN09_07710 | CN09_23610 | CN09_07710 | CN09_23610 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family | 0.975 |
CN09_07710 | CN09_23615 | CN09_07710 | CN09_23615 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | precorrin-3B C17-methyltransferase; Catalyzes the formation of precorrin-4 from precorrin-3B and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
CN09_07710 | CN09_23620 | CN09_07710 | CN09_23620 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | Cobalt-precorrin-6X reductase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
CN09_07710 | cbiE | CN09_07710 | CN09_23625 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | Precorrin-6Y methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
CN09_07710 | cobB | CN09_07710 | CN09_05865 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source | 0.999 |
CN09_07710 | cobH | CN09_07710 | CN09_23605 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | precorrin-8X methylmutase; Catalyzes the interconversion of precorrin-8X and hydrogenobyrinate; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
CN09_07710 | cobM | CN09_07710 | CN09_23630 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family | 0.999 |
CN09_07710 | cobO | CN09_07710 | CN09_05830 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | Cobinamide adenolsyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids | 0.999 |
CN09_07710 | metH | CN09_07710 | CN09_04750 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate | 0.962 |
CN09_23595 | CN09_07710 | CN09_23595 | CN09_07710 | Precorrin 6a synthase; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | 0.966 |
CN09_23595 | CN09_23610 | CN09_23595 | CN09_23610 | Precorrin 6a synthase; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A | precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family | 0.920 |
CN09_23595 | CN09_23615 | CN09_23595 | CN09_23615 | Precorrin 6a synthase; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A | precorrin-3B C17-methyltransferase; Catalyzes the formation of precorrin-4 from precorrin-3B and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.955 |
CN09_23595 | CN09_23620 | CN09_23595 | CN09_23620 | Precorrin 6a synthase; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A | Cobalt-precorrin-6X reductase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.955 |
CN09_23595 | cbiE | CN09_23595 | CN09_23625 | Precorrin 6a synthase; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A | Precorrin-6Y methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
CN09_23595 | cobB | CN09_23595 | CN09_05865 | Precorrin 6a synthase; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source | 0.896 |
CN09_23595 | cobH | CN09_23595 | CN09_23605 | Precorrin 6a synthase; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A | precorrin-8X methylmutase; Catalyzes the interconversion of precorrin-8X and hydrogenobyrinate; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.944 |
CN09_23595 | cobM | CN09_23595 | CN09_23630 | Precorrin 6a synthase; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A | precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family | 0.941 |
CN09_23595 | cobO | CN09_23595 | CN09_05830 | Precorrin 6a synthase; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A | Cobinamide adenolsyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids | 0.841 |
CN09_23610 | CN09_07710 | CN09_23610 | CN09_07710 | precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | 0.975 |