STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CN09_29095ROK family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology (400 aa)    
Predicted Functional Partners:
cpsB
mannose-1-phosphate guanyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family
     
 0.926
gltB
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology
     
 0.871
CN09_03380
2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology
     
 0.836
CN09_29100
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology
 
   
 0.829
CN09_17085
Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family
   
 
 0.825
CN09_29090
ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology
 
     0.824
CN09_29105
Hypothetical protein; Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology
 
     0.799
topA
Dna topoisomerase i; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.738
nnrD
Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]
     
 0.724
CN09_26030
N-methylproline demethylase; Derived by automated computational analysis using gene prediction method: Protein Homology
     
 0.719
Your Current Organism:
Agrobacterium rhizogenes
NCBI taxonomy Id: 359
Other names: A. rhizogenes, ATCC 11325, Agrobacterium biovar 2, Agrobacterium genomic group 10, Agrobacterium genomic species 10, Agrobacterium genomosp. 10, Agrobacterium rhizogenes (RI plasmid PRI1724), Agrobacterium rhizogenes (RI plasmid PRI8196), Agrobacterium rhizogenes (RI plasmid PRIA4B), CFBP 5520, CIP 104328, DSM 30148, ICMP 5794, IFO 13257, JCM 20919, LMG 150, NBRC 13257, NCPPB 2991, Rhizobium rhizogenes, Rhizobium sp. LMG 9509
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