STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CN09_30390Histidine kinase; Member of the two-component regulatory system DctB/DctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates DctD in response to environmental signals (640 aa)    
Predicted Functional Partners:
CN09_30385
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology
 
 
 0.955
CN09_30395
Sulfonate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology
       0.855
CN09_26145
Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology
 
 
 0.767
CN09_25205
Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology
 
 0.738
CN09_30405
Myristoyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology
 
   
 0.657
CN09_30400
Sulfonate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology
       0.591
CN09_21875
Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology
 
 
 0.546
pleD
Response regulator PleD; Involved in swarmer-to-stalked cell differentiation in Caulobacter crescentus; catalyzes the condensation of two GTP molecules to form the secondary messenger cyclic di-GMP (c-di-GMP); upon phosphorylation of domain D1 the protein dimerizes; presumably this allows the two GTP-bound GGDEF (diguanylate cyclase) domains to catalyze the condensation reaction; allosterically inhibited by c-di-GMP; Derived by automated computational analysis using gene prediction method: Protein Homology
 
 
 0.476
CN09_19780
Regulator; Derived by automated computational analysis using gene prediction method: Protein Homology
 
 
 0.448
CN09_23035
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology
 
 
0.436
Your Current Organism:
Agrobacterium rhizogenes
NCBI taxonomy Id: 359
Other names: A. rhizogenes, ATCC 11325, Agrobacterium biovar 2, Agrobacterium genomic group 10, Agrobacterium genomic species 10, Agrobacterium genomosp. 10, Agrobacterium rhizogenes (RI plasmid PRI1724), Agrobacterium rhizogenes (RI plasmid PRI8196), Agrobacterium rhizogenes (RI plasmid PRIA4B), CFBP 5520, CIP 104328, DSM 30148, ICMP 5794, IFO 13257, JCM 20919, LMG 150, NBRC 13257, NCPPB 2991, Rhizobium rhizogenes, Rhizobium sp. LMG 9509
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