STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BAB1_0004NAD binding site:UBA/THIF-type NAD/FAD binding fold:Aromatic-ring hydroxylase. (260 aa)    
Predicted Functional Partners:
BAB1_0217
ThiamineS.
  
 0.992
thiG
FMN/related compound-binding core; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 0.983
moaD
ThiamineS.
  
 0.979
moaE
Molybdopterin biosynthesis MoaE.
 
 0.977
BAB1_0947
Aminotransferase, class V.
 
 
 0.946
BAB2_0344
ATP-dependent protease La, LON.
    
 0.886
BAB1_0219
Eukaryotic/viral aspartic protease, active site:Ribokinase:Phosphomethylpyrimidine kinase.
  
 0.821
BAB1_0215
Thiamine monophosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
 
 
 0.814
trxB
Thioredoxin reductase; Pyridine nucleotide-disulphide oxidoreductase, class-II:Adrenodoxin reductase:Pyridine nucleotide-disulphide oxidoreductase.
  
  
 0.757
BAB1_1900
4Fe-4S ferredoxin, iron-sulfur binding domain:Succinate dehydrogenase/fumarate reductase iron-sulfur protein:2Fe-2S ferredoxin.
 
      0.743
Your Current Organism:
Brucella abortus
NCBI taxonomy Id: 359391
Other names: B. abortus 2308, Brucella abortus 2308, Brucella melitensis biovar Abortus 2308
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