STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BAB1_1036Malic oxidoreductase:Phosphate acetyl/butaryl transferase. (774 aa)    
Predicted Functional Partners:
ackA
Acetate and butyrate kinase:Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
 
 0.983
BAB2_0031
Short-chain dehydrogenase/reductase SDR:Glucose/ribitol dehydrogenase.
  
 
 0.972
glcB
Malate synthase:ATP/GTP-binding site motif A (P-loop):Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
  
 
 0.953
BAB1_1631
Transcriptional regulator, Cro/CI family.
   
 
 0.952
pyk
ATP/GTP-binding site motif A (P-loop):Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.909
mdh
Lactate/malate dehydrogenase:L-lactate dehydrogenase:TrkA potassium uptake protein; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.907
BAB1_1151
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.904
fumC
Fumarate lyase:Delta crystallin:Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.902
BAB1_1467
Auxin Efflux Carrier.
  
  
 0.892
BAB2_0714
Transketolase, central region:Transketolase, C terminal.
  
 
 0.891
Your Current Organism:
Brucella abortus
NCBI taxonomy Id: 359391
Other names: B. abortus 2308, Brucella abortus 2308, Brucella melitensis biovar Abortus 2308
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.