PAS domain:PAS-associated C-terminal domain:PAC motif; Photosensitive kinase that is involved in increased bacterial virulence upon exposure to light. Once ejected from an infected animal host, sunlight acts as an environmental signal that increases the virulence of the bacterium, preparing it for infection of the next host (By similarity). This photoreceptor protein is directly related to the bacterium's survival and replication within host macrophages, as it is required for optimal replication of bacteria inside macrophages.

PAS domain:GGDEF:PAS-associated C-terminal domain:PAC motif:EAL domain.

Na+/solute symporter:Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase A, N-terminal:Bacterial sen.

PAS-associated C-terminal domain.

Response regulator receiver; Essential protein that is involved in the control of cell division, probably through the regulation of ctrA. Its phosphorylation status is regulated by PdhS (By similarity).

Sigma factor, ECF subfamily:Sigma-70 region 2:Sigma-70 region 4.

3,4-Dihydroxy-2-butanone 4-phosphate synthase:GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.

PAS domain:PAC motif:ATP-binding region, ATPase-like:Histidine kinase A, N-terminal:Bacterial sensor protein, C-terminal:Hist.

Cell-division control histidine kinase PdhS; Functions as a polar differentiation marker. Essential protein that, by localizing in the old pole of dividing cells, controls cell division and maturation, probably through control of DivK phosphorylation status and cellular distribution, which in turn regulates CtrA, a transcriptional regulator of the minB operon. The asymmetrical localization of this protein is probably required for cells to enter a new division cycle (By similarity).