STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gcpGlycoprotease (M22) metalloprotease; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (359 aa)    
Predicted Functional Partners:
BAB1_2125
Conserved hypothetical protein.
   
 0.996
BAB1_2151
Glycoprotease (M22) metalloprotease.
  
 
 0.993
BAB1_2102
ATP/GTP-binding site motif A (P-loop):Protein of unknown function UPF0079.
 
 
 0.962
gpsA
Adrenodoxin reductase:NAD-dependent glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
      0.917
BAB1_1892
SAM (and some other nucleotide) binding motif.
 
     0.803
BAB1_1890
YCII-related domain.
       0.800
BAB1_1891
Family of unknown function DUF589.
     
 0.787
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
  
 0.724
BAB1_0434
Sua5/YciO/YrdC/YwlC protein family:SUA5:SUA5/yciO/yrdC, N-terminal; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
  
 
 0.718
leuS
Leucine--tRNA ligase; Aminoacyl-tRNA synthetase, class I:Aminoacyl-tRNA synthetase, class Ia:Leucyl-tRNA synthetase bacterial/mitochondrial, class Ia.
 
 
 
 0.663
Your Current Organism:
Brucella abortus
NCBI taxonomy Id: 359391
Other names: B. abortus 2308, Brucella abortus 2308, Brucella melitensis biovar Abortus 2308
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