Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
aqpZMIP family:Aromatic amino acid permease; Transport of water across the membrane. Possibly involved in the adaptation to variation in intravacuolar pH or osmolarity; Belongs to the MIP/aquaporin (TC 1.A.8) family. (228 aa)    
Predicted Functional Partners:
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 
 0.834
BAB1_0456
Histone deacetylase family.
    
   0.806
BAB2_0245
G-protein beta WD-40 repeat:ATP/GTP-binding site motif A (P-loop).
    
   0.800
glpD
FAD-dependent glycerol-3-phosphate dehydrogenase:FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
  
  
 0.785
eryB
FAD-dependent glycerol-3-phosphate dehydrogenase:FAD dependent oxidoreductase; Catalyzes the oxydation of D-erythritol 1-phosphate to D- erythrulose 1-phosphate.
  
  
 0.785
BAB1_0430
TPR repeat.
    
 
 0.752
BAB1_1760
TPR repeat.
    
 
 0.752
BAB1_0446
Heat shock protein DnaJ, N-terminal:Chaperone DnaJ, C-terminal:Heat shock protein DnaJ.
    
 
 0.742
BAB1_2025
Heat shock protein DnaJ, N-terminal:Heat shock protein DnaJ.
    
 
 0.742
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
    
 
 0.742
Your Current Organism:
Brucella abortus
NCBI taxonomy Id: 359391
Other names: B. abortus 2308, Brucella abortus 2308, Brucella melitensis biovar Abortus 2308
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