STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BAB2_0051Low-specificity threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (349 aa)    
Predicted Functional Partners:
gcvP
Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
 0.828
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.791
gcvT
Glycine cleavage T protein (aminomethyl transferase).
 
 
 0.724
BAB1_0510
Serine/threonine dehydratase, pyridoxal-phosphate attachment site:Pyridoxal-5'-phosphate-dependent enzyme, beta family:Threon.
   
 0.707
BAB2_0935
Short-chain dehydrogenase/reductase SDR:Glucose/ribitol dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
  0.640
BAB2_0285
Aminotransferase class-III.
  
 
 0.632
soxD
Sarcosine oxidase, delta subunit, heterotetrameric.
    
  0.610
BAB1_0349
Aminotransferase, class-II:Aminolevulinic acid synthase:Aminotransferase, class I and II.
     
 0.610
trxB
Thioredoxin reductase; Pyridine nucleotide-disulphide oxidoreductase, class-II:Adrenodoxin reductase:Pyridine nucleotide-disulphide oxidoreductase.
    
  0.603
gltB
Glutamate synthase amidotransferase domain:Glutamate synthase central domain.
     
 0.601
Your Current Organism:
Brucella abortus
NCBI taxonomy Id: 359391
Other names: B. abortus 2308, Brucella abortus 2308, Brucella melitensis biovar Abortus 2308
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