STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
virB10Glutelin:Proline-rich region:Bacterial conjugation TrbI-like protein; The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice. Virb10 seems to be per se essential for intracellular multiplication within non-professional phagocytes and is essential for pathogenesis in mice. (388 aa)    
Predicted Functional Partners:
virB9
Type IV secretion system CagX conjugation protein; The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice; Belongs to the TrbG/VirB9 family.
 0.999
virB8
VirB8; The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice.
 
  
 0.999
virB4
Type IV secretion system protein virB4; The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice; Belongs to the TrbE/VirB4 family.
 
 0.999
virB11
Type IV secretion system protein VirB11; The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice. Virb11 is essential for pathogenesis in mice but is not required for intracellular survival.
  
 0.996
virB6
Type IV secretion system protein VirB6; The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice.
  
 
 0.996
virB7
Type IV secretion system protein VirB7 KO: K03202 type IV secretion system protein VirB7; The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice.
     
 0.995
virB3
Type IV secretory pathway, VirB3-like; The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice.
  
  
 0.991
virB1
SLT domain; The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice; Belongs to the virb1 family.
 
   
 0.947
virB2
Type IV secretion system protein VirB2 KO: K03197 type IV secretion system protein VirB2; The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice.
  
  
 0.940
virB5
Attachment mediating protein virB5 homolog KO: K03200 type IV secretion system protein VirB5; The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice; Belongs to the virb5 family.
    
 0.879
Your Current Organism:
Brucella abortus
NCBI taxonomy Id: 359391
Other names: B. abortus 2308, Brucella abortus 2308, Brucella melitensis biovar Abortus 2308
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