Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
eryIRibose/galactose isomerase; Catalyzes the isomerization of D-erythrulose-4P to D- erythrose-4P. Involved in the degradation pathway of erythritol, that allows B.abortus to grow on this compound as the sole carbon source. Belongs to the LacAB/RpiB family. (151 aa)    
Predicted Functional Partners:
tpiA-2
Cyclic nucleotide-binding domain:Triosephosphate isomerase; Catalyzes the isomerization of D-erythrulose-4P to L- erythrulose-1P. Involved in the degradation pathway of erythritol, that allows B.abortus to grow on this compound as the sole carbon source. Belongs to the triosephosphate isomerase family.
  
 0.985
eryA
Carbohydrate kinase, FGGY; Catalyzes the phosphorylation of erythritol to D-erythritol- 1-phosphate.
 
  
 0.930
eryC
D-erythrulose 4-phosphate dehydrogenase; Catalyzes the racemization of D-erythrulose 1-phosphate to L- erythrulose 1-phosphate.
 
   
 0.916
eryD
Putative sugar-binding domain; Represses the expression of the eryABCD operon, which is involved in erythritol catabolism; Belongs to the SorC transcriptional regulatory family.
 
   
 0.900
BAB2_0368
Bacterial regulatory protein, DeoR family.
 
  
 0.895
BAB2_1027
Phosphoribosyltransferase:Uracil phosphoribosyl transferase; Belongs to the UPRTase family.
 
    0.871
gcvP
Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
 0.801
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
    
 0.792
rpe
Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
  
 
 0.791
BAB1_0188
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.789
Your Current Organism:
Brucella abortus
NCBI taxonomy Id: 359391
Other names: B. abortus 2308, Brucella abortus 2308, Brucella melitensis biovar Abortus 2308
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