STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eryIRibose/galactose isomerase; Catalyzes the isomerization of D-erythrulose-4P to D- erythrose-4P. Involved in the degradation pathway of erythritol, that allows B.abortus to grow on this compound as the sole carbon source. Belongs to the LacAB/RpiB family. (151 aa)    
Predicted Functional Partners:
tpiA-2
Cyclic nucleotide-binding domain:Triosephosphate isomerase; Catalyzes the isomerization of D-erythrulose-4P to L- erythrulose-1P. Involved in the degradation pathway of erythritol, that allows B.abortus to grow on this compound as the sole carbon source. Belongs to the triosephosphate isomerase family.
 
 0.986
eryA
Carbohydrate kinase, FGGY; Catalyzes the phosphorylation of erythritol to D-erythritol- 1-phosphate.
 
  
 0.939
BAB2_0368
Bacterial regulatory protein, DeoR family.
 
 
 0.921
eryD
Putative sugar-binding domain; Represses the expression of the eryABCD operon, which is involved in erythritol catabolism; Belongs to the SorC transcriptional regulatory family.
 
   
 0.912
eryC
D-erythrulose 4-phosphate dehydrogenase; Catalyzes the racemization of D-erythrulose 1-phosphate to L- erythrulose 1-phosphate.
 
   
 0.911
BAB2_1027
Phosphoribosyltransferase:Uracil phosphoribosyl transferase; Belongs to the UPRTase family.
 
    0.876
BAB2_0031
Short-chain dehydrogenase/reductase SDR:Glucose/ribitol dehydrogenase.
  
 
 0.818
tal
Transaldolase:Transaldolase C; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.793
gap
Glyceraldehyde 3-phosphate dehydrogenase:TrkA potassium uptake protein:Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
  
 0.788
gcvP
Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
 0.765
Your Current Organism:
Brucella abortus
NCBI taxonomy Id: 359391
Other names: B. abortus 2308, Brucella abortus 2308, Brucella melitensis biovar Abortus 2308
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