STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eryDPutative sugar-binding domain; Represses the expression of the eryABCD operon, which is involved in erythritol catabolism; Belongs to the SorC transcriptional regulatory family. (316 aa)    
Predicted Functional Partners:
eryC
D-erythrulose 4-phosphate dehydrogenase; Catalyzes the racemization of D-erythrulose 1-phosphate to L- erythrulose 1-phosphate.
 
   
 0.971
eryA
Carbohydrate kinase, FGGY; Catalyzes the phosphorylation of erythritol to D-erythritol- 1-phosphate.
 
  
 0.966
tpiA-2
Cyclic nucleotide-binding domain:Triosephosphate isomerase; Catalyzes the isomerization of D-erythrulose-4P to L- erythrulose-1P. Involved in the degradation pathway of erythritol, that allows B.abortus to grow on this compound as the sole carbon source. Belongs to the triosephosphate isomerase family.
 
  
 0.930
eryI
Ribose/galactose isomerase; Catalyzes the isomerization of D-erythrulose-4P to D- erythrose-4P. Involved in the degradation pathway of erythritol, that allows B.abortus to grow on this compound as the sole carbon source. Belongs to the LacAB/RpiB family.
 
   
 0.912
eryB
FAD-dependent glycerol-3-phosphate dehydrogenase:FAD dependent oxidoreductase; Catalyzes the oxydation of D-erythritol 1-phosphate to D- erythrulose 1-phosphate.
    
 0.900
BAB2_0374
Conserved hypothetical protein.
 
     0.785
BAB2_0368
Bacterial regulatory protein, DeoR family.
 
   
 0.763
rbsB-2
Periplasmic binding protein/LacI transcriptional regulator.
 
  
 0.684
BAB2_0373
Conserved hypothetical protein.
       0.675
gpsA
Adrenodoxin reductase:NAD-dependent glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
    
  0.592
Your Current Organism:
Brucella abortus
NCBI taxonomy Id: 359391
Other names: B. abortus 2308, Brucella abortus 2308, Brucella melitensis biovar Abortus 2308
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