Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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BAB2_0652PAS domain:PAS-associated C-terminal domain:PAC motif; Photosensitive kinase that is involved in increased bacterial virulence upon exposure to light. Once ejected from an infected animal host, sunlight acts as an environmental signal that increases the virulence of the bacterium, preparing it for infection of the next host (By similarity). This photoreceptor protein is directly related to the bacterium's survival and replication within host macrophages, as it is required for optimal replication of bacteria inside macrophages. (463 aa)    
Predicted Functional Partners:
BAB1_0346
Na+/solute symporter:Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase A, N-terminal:Bacterial sen.
  
 0.991
BAB1_0507
PAS domain:GGDEF:PAS-associated C-terminal domain:PAC motif:EAL domain.
 0.953
BAB1_1673
ATP-binding region, ATPase-like:Histidine kinase.
 
  
 0.938
BAB1_1671
Response regulator receiver.
 
 0.937
BAB1_0220
PAS domain:GGDEF:PAS-associated C-terminal domain:PAC motif:EAL domain.
 
 0.914
BAB1_0328
ATP-binding region, ATPase-like:Histidine kinase A, N-terminal:Bacterial sensor protein, C-terminal:Histidine kinase.
  
 0.808
BAB2_0630
GGDEF:Response regulator receiver.
  
 0.774
BAB1_0099
Response regulator receiver.
 
   
 0.756
BAB2_0041
Bacterial regulatory protein, LuxR family:Response regulator receiver.
 
 
 0.748
pdhS
Cell-division control histidine kinase PdhS; Functions as a polar differentiation marker. Essential protein that, by localizing in the old pole of dividing cells, controls cell division and maturation, probably through control of DivK phosphorylation status and cellular distribution, which in turn regulates CtrA, a transcriptional regulator of the minB operon. The asymmetrical localization of this protein is probably required for cells to enter a new division cycle (By similarity).
   
 0.737
Your Current Organism:
Brucella abortus
NCBI taxonomy Id: 359391
Other names: B. abortus 2308, Brucella abortus 2308, Brucella melitensis biovar Abortus 2308
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