Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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ackAAcetate and butyrate kinase:Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (401 aa)    
Predicted Functional Partners:
BAB2_0836
D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase.
  
 0.987
BAB1_1036
Malic oxidoreductase:Phosphate acetyl/butaryl transferase.
  
 
 0.973
BAB1_1631
Transcriptional regulator, Cro/CI family.
   
 
 0.931
glcB
Malate synthase:ATP/GTP-binding site motif A (P-loop):Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 
 0.910
acsA
AMP-dependent synthetase and ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
     
 0.852
lldD
FMN-dependent alpha-hydroxy acid dehydrogenase:FMN/related compound-binding core.
     
 0.782
BAB2_0031
Short-chain dehydrogenase/reductase SDR:Glucose/ribitol dehydrogenase.
  
 
 0.781
BAB1_1151
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.770
BAB1_1077
Acetyl-CoA hydrolase/transferase.
     
 0.761
BAB1_1744
AMP-dependent synthetase and ligase.
     
 0.717
Your Current Organism:
Brucella abortus
NCBI taxonomy Id: 359391
Other names: B. abortus 2308, Brucella abortus 2308, Brucella melitensis biovar Abortus 2308
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