Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nnrRCyclic nucleotide-binding domain:Bacterial regulatory protein, Crp family. (232 aa)    
Predicted Functional Partners:
gltB
Glutamate synthase amidotransferase domain:Glutamate synthase central domain.
    
 0.821
BAB2_0921
Blue (type 1) copper domain:Blue (type 1) copper protein:Amicyanin:Plastocyanin.
 
     0.820
BAB2_0920
Conserved hypothetical protein.
 
   
 0.729
BAB2_0943
Multicopper oxidase, type 1:Copper-containing nitrite reductase:Twin-arginine translocation pathway signal; Belongs to the multicopper oxidase family.
  
   
 0.722
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.717
rpoA
RNA polymerase, alpha chain, bacterial and organelle; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.711
rpoC
RNA polymerase, alpha subunit:RNA polymerase I subunit A, N-terminal:RNA polymerase Rpb1, domain 1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.709
rpoZ
RNA polymerase, omega subunit:RNA polymerase Rpb6; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.704
BAB1_2005
Cyclic nucleotide-binding domain:cAMP-dependent protein kinase:Delta crystallin.
  
  
  0.703
BAB1_0346
Na+/solute symporter:Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase A, N-terminal:Bacterial sen.
  
 0.697
Your Current Organism:
Brucella abortus
NCBI taxonomy Id: 359391
Other names: B. abortus 2308, Brucella abortus 2308, Brucella melitensis biovar Abortus 2308
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