STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glkGlucokinase:Inorganic pyrophosphatase; Belongs to the bacterial glucokinase family. (343 aa)    
Predicted Functional Partners:
BAB2_0494
Helix-turn-helix protein RpiR:Bacterial regulatory protein LacI, HTH motif:Sugar isomerase (SIS).
   
 0.942
zwf
Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
 0.940
pgl
6- phosphogluconolactonase:Glucosamine/galactosamine-6- phosphate isomerase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
 
 0.919
edd
Dihydroxy-acid and 6-phosphogluconate dehydratase:6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.
 
 
 0.903
pgi
Phosphoglucose isomerase (PGI); Belongs to the GPI family.
    
 0.872
BAB2_0083
KDPG and KHG aldolase.
 
 
 0.842
mepA
Peptidase family U6, penicillin-insensitive murein endopeptidase.
   
 0.836
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
    
 0.746
BAB2_0296
KDPG and KHG aldolase.
  
 
 0.725
tal
Transaldolase:Transaldolase C; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
    
 0.723
Your Current Organism:
Brucella abortus
NCBI taxonomy Id: 359391
Other names: B. abortus 2308, Brucella abortus 2308, Brucella melitensis biovar Abortus 2308
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