STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
EAT98805.1Putative dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (213 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
 
 
 0.967
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 0.950
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 0.929
EAT97588.1
Putative nucleotide phosphoribosyltransferase; Pfam match to PF00156.22 Pribosyltran.
 
 
  0.914
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
 
    0.908
surE
Broad specificity 5'(3')-nucleotidase and polyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
  0.900
EAT99380.1
Metallophosphatase; Pfam matches to PF12850.2 Metallophos_2, and to PF00149.23 Metallophos.
  
  
 0.829
nusG
Transcription antitermination protein; Participates in transcription elongation, termination and antitermination.
   
    0.631
folE
Pfam match to PF01227.17 GTP_cyclohydroI.
  
  
 0.607
EAT98884.1
Putative sugar transporter, major facilitator superfamily; Pfam matches to PF07690.11 MFS_1, and to PF07690.11 MFS_1, and to PF00083.19 Sugar_tr.
       0.596
Your Current Organism:
Campylobacter concisus
NCBI taxonomy Id: 360104
Other names: C. concisus 13826, Campylobacter concisus 13826, Campylobacter concisus str. 13826, Campylobacter concisus strain 13826
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