node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
adk | apt | CCV52592_0466 | CCV52592_1315 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.945 |
adk | gmk | CCV52592_0466 | CCV52592_1256 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Deoxyguanylate kinase / guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.821 |
adk | guaA | CCV52592_0466 | CCV52592_0940 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.624 |
adk | guaB | CCV52592_0466 | CCV52592_0979 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.438 |
adk | purB | CCV52592_0466 | CCV52592_1121 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Pfam matches to PF00206.15 Lyase_1, and to PF10397.4 ADSL_C; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.935 |
adk | pyrH | CCV52592_0466 | CCV52592_0481 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.571 |
adk | surE | CCV52592_0466 | CCV52592_1650 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Broad specificity 5'(3')-nucleotidase and polyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.917 |
apt | adk | CCV52592_1315 | CCV52592_0466 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.945 |
apt | gmk | CCV52592_1315 | CCV52592_1256 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Deoxyguanylate kinase / guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.968 |
apt | guaA | CCV52592_1315 | CCV52592_0940 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.995 |
apt | guaB | CCV52592_1315 | CCV52592_0979 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.687 |
apt | purB | CCV52592_1315 | CCV52592_1121 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Pfam matches to PF00206.15 Lyase_1, and to PF10397.4 ADSL_C; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.940 |
apt | purH | CCV52592_1315 | CCV52592_1838 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | AICAR transformylase / IMP cyclohydrolase; Bifunctional; Pfam matches to PF01808.13 AICARFT_IMPCHas, and to PF02142.17 MGS. | 0.964 |
apt | surE | CCV52592_1315 | CCV52592_1650 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Broad specificity 5'(3')-nucleotidase and polyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.915 |
gmk | adk | CCV52592_1256 | CCV52592_0466 | Deoxyguanylate kinase / guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.821 |
gmk | apt | CCV52592_1256 | CCV52592_1315 | Deoxyguanylate kinase / guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.968 |
gmk | guaA | CCV52592_1256 | CCV52592_0940 | Deoxyguanylate kinase / guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.971 |
gmk | guaB | CCV52592_1256 | CCV52592_0979 | Deoxyguanylate kinase / guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.624 |
gmk | pyrH | CCV52592_1256 | CCV52592_0481 | Deoxyguanylate kinase / guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.728 |
gmk | surE | CCV52592_1256 | CCV52592_1650 | Deoxyguanylate kinase / guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Broad specificity 5'(3')-nucleotidase and polyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.918 |