STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pthpeptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (181 aa)    
Predicted Functional Partners:
rplY
50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
 
    0.911
ychF
GTP-binding protein, putative GTP-dependent translation factor; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
 
  
 0.890
EAU01011.1
Putative lipooligosaccharide transport system, permease component (LptG family); Pfam match to PF03739.9 YjgP_YjgQ.
       0.800
dxs
1-deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
     
 0.700
prfB
Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
 
  
 0.692
pheA
Chorismate mutase / prephenate dehydratase; Bifunctional; Pfam matches to PF00800.13 PDT, and to PF01817.16 CM_2, and to PF01842.20 ACT.
       0.682
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
  
  
 0.672
cmeR
Multidrug efflux system CmeABC transcriptional regulator, TetR family; Pfam match to PF00440.18 TetR_N.
  
    0.665
cheA
Chemotaxis sensory histidine kinase; Pfam matches to PF00072.19 Response_reg, and to PF01584.14 CheW, and to PF02518.21 HATPase_c, and to PF02895.9 H-kinase_dim, and to PF01627.18 Hpt.
       0.658
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
       0.651
Your Current Organism:
Campylobacter curvus
NCBI taxonomy Id: 360105
Other names: C. curvus 525.92, Campylobacter curvus 525.92, Campylobacter curvus str. 525.92, Campylobacter curvus strain 525.92
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