node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABS50937.1 | glyA | CHAB381_1170 | CHAB381_1647 | 5-methyltetrahydropteroyltriglutamate-- homocystei ne methyltransferase; Identified by match to protein family HMM PF01717; match to protein family HMM PF08267. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.452 |
ABS50937.1 | metG | CHAB381_1170 | CHAB381_0727 | 5-methyltetrahydropteroyltriglutamate-- homocystei ne methyltransferase; Identified by match to protein family HMM PF01717; match to protein family HMM PF08267. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.911 |
ABS50937.1 | metK | CHAB381_1170 | CHAB381_1103 | 5-methyltetrahydropteroyltriglutamate-- homocystei ne methyltransferase; Identified by match to protein family HMM PF01717; match to protein family HMM PF08267. | Methionine adenosyltransferase; Identified by match to protein family HMM PF00438; match to protein family HMM PF02772; match to protein family HMM PF02773; match to protein family HMM TIGR01034; Belongs to the AdoMet synthase family. | 0.971 |
ABS52321.1 | metK | CHAB381_0056 | CHAB381_1103 | Cytosine-specific methyltransferase NlaX (M.NlaX); Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Methionine adenosyltransferase; Identified by match to protein family HMM PF00438; match to protein family HMM PF02772; match to protein family HMM PF02773; match to protein family HMM TIGR01034; Belongs to the AdoMet synthase family. | 0.906 |
glyA | ABS50937.1 | CHAB381_1647 | CHAB381_1170 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 5-methyltetrahydropteroyltriglutamate-- homocystei ne methyltransferase; Identified by match to protein family HMM PF01717; match to protein family HMM PF08267. | 0.452 |
glyA | guaA | CHAB381_1647 | CHAB381_0638 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Gmp synthase [glutamine-hydrolyzing] (glutamineamidotransferase) (gmp synthetase) (gmps); Catalyzes the synthesis of GMP from XMP. | 0.606 |
glyA | metG | CHAB381_1647 | CHAB381_0727 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.633 |
glyA | metK | CHAB381_1647 | CHAB381_1103 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Methionine adenosyltransferase; Identified by match to protein family HMM PF00438; match to protein family HMM PF02772; match to protein family HMM PF02773; match to protein family HMM TIGR01034; Belongs to the AdoMet synthase family. | 0.679 |
glyA | purF | CHAB381_1647 | CHAB381_1359 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.817 |
glyA | tpiA | CHAB381_1647 | CHAB381_0779 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.426 |
guaA | glyA | CHAB381_0638 | CHAB381_1647 | Gmp synthase [glutamine-hydrolyzing] (glutamineamidotransferase) (gmp synthetase) (gmps); Catalyzes the synthesis of GMP from XMP. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.606 |
guaA | metG | CHAB381_0638 | CHAB381_0727 | Gmp synthase [glutamine-hydrolyzing] (glutamineamidotransferase) (gmp synthetase) (gmps); Catalyzes the synthesis of GMP from XMP. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.825 |
guaA | metK | CHAB381_0638 | CHAB381_1103 | Gmp synthase [glutamine-hydrolyzing] (glutamineamidotransferase) (gmp synthetase) (gmps); Catalyzes the synthesis of GMP from XMP. | Methionine adenosyltransferase; Identified by match to protein family HMM PF00438; match to protein family HMM PF02772; match to protein family HMM PF02773; match to protein family HMM TIGR01034; Belongs to the AdoMet synthase family. | 0.638 |
guaA | purF | CHAB381_0638 | CHAB381_1359 | Gmp synthase [glutamine-hydrolyzing] (glutamineamidotransferase) (gmp synthetase) (gmps); Catalyzes the synthesis of GMP from XMP. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.714 |
metG | ABS50937.1 | CHAB381_0727 | CHAB381_1170 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 5-methyltetrahydropteroyltriglutamate-- homocystei ne methyltransferase; Identified by match to protein family HMM PF01717; match to protein family HMM PF08267. | 0.911 |
metG | glyA | CHAB381_0727 | CHAB381_1647 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.633 |
metG | guaA | CHAB381_0727 | CHAB381_0638 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Gmp synthase [glutamine-hydrolyzing] (glutamineamidotransferase) (gmp synthetase) (gmps); Catalyzes the synthesis of GMP from XMP. | 0.825 |
metG | metK | CHAB381_0727 | CHAB381_1103 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Methionine adenosyltransferase; Identified by match to protein family HMM PF00438; match to protein family HMM PF02772; match to protein family HMM PF02773; match to protein family HMM TIGR01034; Belongs to the AdoMet synthase family. | 0.630 |
metG | msrA | CHAB381_0727 | CHAB381_1085 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Peptide methionine sulfoxide reductase MsrA/msrB; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.701 |
metG | purF | CHAB381_0727 | CHAB381_1359 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.634 |