STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAP12813.13-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. (437 aa)    
Predicted Functional Partners:
GAP14408.1
Mevalonate kinase.
 0.997
GAP12811.1
hydroxymethylglutaryl-CoA synthase.
 
 
 0.995
GAP12636.1
1,4-dihydroxy-2-naphthoate octaprenyltransferase.
    
 
 0.963
GAP15195.1
1,4-dihydroxy-2-naphthoate octaprenyltransferase.
    
 
 0.963
GAP15504.1
1,4-dihydroxy-2-naphthoate octaprenyltransferase.
    
 
 0.963
menA
1,4-dihydroxy-2-naphthoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
    
 
 0.963
GAP15072.1
Diphosphomevalonate decarboxylase.
 
 
 0.927
GAP13111.1
acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family.
 
  
 0.925
fni
Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
   
 0.856
GAP14552.1
ATPases of the AAA+ class.
    
 
 0.717
Your Current Organism:
Longilinea arvoryzae
NCBI taxonomy Id: 360412
Other names: JCM 13670, KTCC 5380, L. arvoryzae, Longilinea arvoryzae Yamada et al. 2007, anaerobic filamentous bacterium KOME-1, strain KOME-1
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