node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GAP15125.1 | GAP15156.1 | LARV_02906 | LARV_02938 | Protein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Membrane protein insertase, YidC/Oxa1 family, C-terminal domain. | 0.997 |
GAP15125.1 | ffh | LARV_02906 | LARV_02166 | Protein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle subunit FFH/SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.994 |
GAP15125.1 | rplA | LARV_02906 | LARV_00878 | Protein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | LSU ribosomal protein L1P; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.982 |
GAP15125.1 | rplJ | LARV_02906 | LARV_00880 | Protein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | LSU ribosomal protein L10P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.968 |
GAP15125.1 | rplK | LARV_02906 | LARV_00877 | Protein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.983 |
GAP15125.1 | rplM | LARV_02906 | LARV_03078 | Protein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.993 |
GAP15125.1 | secA | LARV_02906 | LARV_03195 | Protein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.999 |
GAP15125.1 | secE | LARV_02906 | LARV_00875 | Protein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, SecE subunit, bacterial; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.999 |
GAP15125.1 | secY | LARV_02906 | LARV_03087 | Protein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.999 |
GAP15156.1 | GAP15125.1 | LARV_02938 | LARV_02906 | Membrane protein insertase, YidC/Oxa1 family, C-terminal domain. | Protein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.997 |
GAP15156.1 | ffh | LARV_02938 | LARV_02166 | Membrane protein insertase, YidC/Oxa1 family, C-terminal domain. | Signal recognition particle subunit FFH/SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.924 |
GAP15156.1 | rplA | LARV_02938 | LARV_00878 | Membrane protein insertase, YidC/Oxa1 family, C-terminal domain. | LSU ribosomal protein L1P; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.757 |
GAP15156.1 | rplK | LARV_02938 | LARV_00877 | Membrane protein insertase, YidC/Oxa1 family, C-terminal domain. | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.750 |
GAP15156.1 | rplM | LARV_02938 | LARV_03078 | Membrane protein insertase, YidC/Oxa1 family, C-terminal domain. | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.970 |
GAP15156.1 | rpsD | LARV_02938 | LARV_03082 | Membrane protein insertase, YidC/Oxa1 family, C-terminal domain. | SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.542 |
GAP15156.1 | secA | LARV_02938 | LARV_03195 | Membrane protein insertase, YidC/Oxa1 family, C-terminal domain. | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.950 |
GAP15156.1 | secE | LARV_02938 | LARV_00875 | Membrane protein insertase, YidC/Oxa1 family, C-terminal domain. | Preprotein translocase, SecE subunit, bacterial; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.995 |
GAP15156.1 | secY | LARV_02938 | LARV_03087 | Membrane protein insertase, YidC/Oxa1 family, C-terminal domain. | Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.998 |
ffh | GAP15125.1 | LARV_02166 | LARV_02906 | Signal recognition particle subunit FFH/SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Protein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.994 |
ffh | GAP15156.1 | LARV_02166 | LARV_02938 | Signal recognition particle subunit FFH/SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Membrane protein insertase, YidC/Oxa1 family, C-terminal domain. | 0.924 |