STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
csrA_1Carbon storage regulator homolog; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. (72 aa)    
Predicted Functional Partners:
fliW
Flagellar assembly factor FliW; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
 
 
 0.999
flgL
Hook-filament junction protein.
 
  
 0.938
flgB
Flagellar basal body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
 
  
 0.891
fliS
Flagellar protein fliS.
 
  
 0.878
flgM
Flagellar biosynthesis anti-sigma factor FlgM.
  
  
 0.878
flgK_2
Flagellar hook-associated protein 1.
 
  
 0.860
fliF
Flagellar M-ring protein.
  
  
 0.840
fliD
Flagellar cap protein.
 
  
 0.839
fliC
Phase 1-I flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
 
  
 0.817
flgK_1
Flagellar hook-associated protein 1; Belongs to the flagella basal body rod proteins family.
 
  
 0.799
Your Current Organism:
Roseburia inulinivorans
NCBI taxonomy Id: 360807
Other names: DSM 16841, NCIMB 14030, R. inulinivorans, Roseburia inulinivorans Duncan et al. 2006, butyrate-producing bacterium A2-194, butyrate-producing bacterium L1-83, strain A2-194
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.