STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CUO01111.1sigma-E processing peptidase SpoIIGA. (261 aa)    
Predicted Functional Partners:
spoIIE
Stage II sporulation protein E.
  
  
 0.941
sigE
Stage II sporulation protein GB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.913
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.873
CUN59103.1
Stage II sporulation protein P.
  
   
 0.739
spoIIR
Stage II sporulation protein R.
 
   
 0.738
sigF_2
Stage II sporulation protein AC; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.727
spoIIAA
Stage II sporulation protein AA; Belongs to the anti-sigma-factor antagonist family.
  
  
 0.720
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
     
 0.709
CUN80058.1
Uncharacterized protein conserved in bacteria.
  
   
 0.692
CUN82412.1
Sporulation protein YqfD.
  
   
 0.682
Your Current Organism:
Roseburia inulinivorans
NCBI taxonomy Id: 360807
Other names: DSM 16841, NCIMB 14030, R. inulinivorans, Roseburia inulinivorans Duncan et al. 2006, butyrate-producing bacterium A2-194, butyrate-producing bacterium L1-83, strain A2-194
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.