STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A077ZCM8EfThoc1 and Death domain containing protein. (725 aa)    
Predicted Functional Partners:
A0A077ZF34
Tho2 and Thoc2 domain containing protein.
   
 0.999
A0A077Z7L6
THO complex subunit 6 protein.
    
 0.996
A0A077ZK38
WD40 domain containing protein.
    
 0.988
A0A077ZK86
WD40 domain containing protein.
    
 0.988
A0A077YVA1
Spliceosome RNA helicase DDX39B.
   
 0.987
A0A077ZFF8
THO complex subunit 4.
    
 0.974
A0A077YZU7
Nuclear RNA export factor 1.
    
 0.837
A0A077YWF0
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. In the CBC complex, ncbp-2 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp-1 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure.
    
 0.834
A0A077ZBZ7
Cap binding protein 80.
    
 0.824
A0A077ZDX8
Uncharacterized protein.
    
 0.796
Your Current Organism:
Trichuris trichiura
NCBI taxonomy Id: 36087
Other names: T. trichiura, human whipworm
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