STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
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Coexpression
Experiments
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[Homology]
Score
metKS-adenosylmethionine synthetase; Start codon not provided; Belongs to the AdoMet synthase family. (387 aa)    
Predicted Functional Partners:
metE
Putative 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase.
  
 0.966
metE-2
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 0.966
metH
Methionine synthase (5-methyltetrahydrofolate--homocysteine methyltransferase); Start codon not provided.
  
 
 0.964
BAV1283
Putative phage methyltransferase.
    
 0.916
tyrB
Aromatic-amino-acid aminotransferase.
     
 0.909
BAV0109
Conserved hypothetical protein.
     
  0.900
acyH
Adenosylhomocysteinase; Start codon not provided.
 
 
 0.874
metF
5,10-methylenetetrahydrofolate reductase; Deleted EC_number 1.7.99.5; Belongs to the methylenetetrahydrofolate reductase family.
  
  
 0.830
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
 
  
 0.796
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.793
Your Current Organism:
Bordetella avium
NCBI taxonomy Id: 360910
Other names: B. avium 197N, Bordetella avium 197N, Bordetella avium str. 197N, Bordetella avium strain 197N
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.