STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (432 aa)    
Predicted Functional Partners:
bllY
4-hydroxyphenylpyruvate dioxygenase (putative hemolysin).
 
 0.997
fahA
Fumarylacetoacetase.
 
  
 0.988
nagL
Maleylpyruvate isomerase (glutathione S-transferase).
 
 
 0.906
maaI
Maleylacetoacetate isomerase (glutathione-S-transferase).
 
 
 0.906
BAV0690
Pterin-4-alpha-carbinolamine dehydratase.
 
  
 0.758
BAV0531
Putative oxygenase; Start codon not provided.
 
  
 0.628
BAV0530
Conserved hypothetical protein.
 
     0.612
BAV3126
Putative monooxygenase.
 
  
 0.603
BAV0529
LysR-family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
       0.536
BAV0614
Putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase.
  
  
 0.520
Your Current Organism:
Bordetella avium
NCBI taxonomy Id: 360910
Other names: B. avium 197N, Bordetella avium 197N, Bordetella avium str. 197N, Bordetella avium strain 197N
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