STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
bphC2,3-dihydroxybiphenyl 1,2-dioxygenase. (301 aa)    
Predicted Functional Partners:
BAV0595
Pigment production hydroxylase.
 
   
 0.907
bphD
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase.
 
  
 0.843
bphG
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
   
 0.784
bphF
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
   
 0.772
BAV0596
Putative monooxygenase/oxidoreductase.
 
  
 0.765
bphE
2-keto-4-pentenoate hydratase; Start codon not provided.
 
   
 0.729
BAV0607
TetR-family transcriptional regulator.
 
   
 0.524
BAV3258
Putative dehydrogenase; Similarity to kstd2 is limited to the C-terminus.
  
   0.521
BAV3254
Putative reductase flavoprotein subunit; Also similar to BAV0956 (29.2 38d); Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
   0.466
BAV0609
Putative iron-sulphur containing oxygenase.
 
   
 0.464
Your Current Organism:
Bordetella avium
NCBI taxonomy Id: 360910
Other names: B. avium 197N, Bordetella avium 197N, Bordetella avium str. 197N, Bordetella avium strain 197N
Server load: low (16%) [HD]