STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bphE2-keto-4-pentenoate hydratase; Start codon not provided. (266 aa)    
Predicted Functional Partners:
bphF
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 
 0.991
bphD
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase.
 
 
 0.972
bphG
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
  
 0.959
BAV0595
Pigment production hydroxylase.
 
   
 0.731
bphC
2,3-dihydroxybiphenyl 1,2-dioxygenase.
 
   
 0.729
BAV1269
Putative catechol 2,3-dioxygenase (metapyrocatechase).
 
   
 0.727
hpaF
5-carboxymethyl-2-hydroxymuconate delta-isomerase.
 
  
 0.646
BAV1616
Putative hydratase.
  
     0.641
BAV0601
Conserved hypothetical protein; Start codon not provided.
       0.588
amnB
2-aminophenol 1,6-dioxygenase beta subunit.
 
  
 0.511
Your Current Organism:
Bordetella avium
NCBI taxonomy Id: 360910
Other names: B. avium 197N, Bordetella avium 197N, Bordetella avium str. 197N, Bordetella avium strain 197N
Server load: low (28%) [HD]